Montelukast improves regional air-trapping due to small airways obstruction in asthma
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منابع مشابه
Montelukast improves regional air-trapping due to small airways obstruction in asthma.
Quantitative image analysis of high-resolution computed tomography (HRCT) performed at residual volume, before and after methacholine, is a sensitive method of detecting small airways involvement in asthma and response to therapy targeted to the small airways. Since an oral anti-leukotriene reaches the small airways via the circulation, the present authors hypothesised that treatment with monte...
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Asthma is a lung disease characterized by inflammation and remodeling of the airways. It is now widely accepted that airway inflammation and remodeling occur not only in the central airways but also in the small airways and even in the lung parenchyma. Inflammation of the distal lung can be observed even in mild asthmatics with normal or noncompromised lung function. Moreover, the small airways...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2006
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.06.00005605